Hi, the substances you’ve been taking are not to be used with ayahuasca (especially Propanolol which works with tryptamine and can affect blood pressure during ayahuasca session), but since you’ve been stopping taking it for a certain period of time (4 weeks minimum) it shouldn’t be a problem. The most dangerous drugs interactions are antidepressants based on benzodiazepine which create a serotonin syndrome. All drugs increasing serotonin levels or serotonin receptors must be stopped at least 6 weeks before ayahuasca.

I hope to do my first Aya ceremony in about 4 weeks and I was wondering if you know if the medications I’m taking would have any effect or interactions with Aya?

I take either Hydroxizine (antihistamine and sedative) or Propanolol (beta-blocker) for anxiety on an SOS basis. I haven’t taken the meds for at least a week now and I don’t plan to take any until the ceremony.

I also took Desloratidine (antihistamine) about 45 days ago.

Will there be any risk involved if I don’t take these meds for the next 4 weeks?

Hi,
thanks for your interest in Amazonian medicine. Ayahuasca consumption is dangerous with serious hypertension/hypotension, strong heart arrhythmia, any surgery on heart such as bypass surgery. Most of the time people with these affections need to take also daily medication like beta-blockers which are contra-indicated. Your case look different. You’re 24 years old, your body is strong you’re practicing sport, your heart must be in good state. If you’re not medicated with something contra-indicated or if your are not having hypertension I don’t see why you couldn’t take Ayahuasca. Nevertheless I don’t recommend you to do emetics sessions with toxic plants such as tobacco. Emetics are often gaven before drinking ayahuasca to prepare the body. Few people die already by taking tobacco juice because of the nicotine, they had an heart attack.